Brian Meshkin
Brian Meshkin
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Making a Difference

Making a DifferenceMaking a DifferenceMaking a Difference

A Life's Journey to Change Things for the Better

Making a Difference

Making a DifferenceMaking a DifferenceMaking a Difference

A Life's Journey to Change Things for the Better

Award-Winning Technology Entrepreneur & Executive

High-Growth Executive

Strong Technology Leader

Strong Technology Leader

Founded and led the nation’s fastest growing precision medicine company – two years listed on the Inc. 500 and 5000 

Strong Technology Leader

Strong Technology Leader

Strong Technology Leader

Founded and led one of the fastest growing technology companies in North America in the health technology field 

Award-Winning CEO

Strong Technology Leader

Recognized Researcher

Emerging Technology Company CEO of the Year in 2016, OC Business Journal Excellence in Entrepreneurship Award Winner, 3-Time winner of the SmartCEO Future50 Award, & More 

Recognized Researcher

Successful Entrepreneur

Recognized Researcher

Recognized by various medical societies including the American Academy of Pediatrics (AAP), ASIPP, ASRA, AAN and more 

Successful Entrepreneur

Successful Entrepreneur

Successful Entrepreneur

Two-time finalist for the EY Entrepreneur of the Year Award in Orange County, California 

Social Impact Investor

Successful Entrepreneur

Successful Entrepreneur

Managing Director of Profound Ventures, a social entrepreneurship fund supporting the growth of models and technologies whose mission is to solve profound societal problems

Lifetime of Serving Others

Saving the Lives of Children

Saving the Lives of Children

Saving the Lives of Children

At 13 years of age following the tragic death of a friend, Brian led the effort to enact the nation’s 1st bicycle helmet law for children. 

Effective Policy Advocate

Saving the Lives of Children

Saving the Lives of Children

While in high school, Brian worked with many groups to successfully lobby for over 300 child safety laws enacted across the U.S. 

Community Activist

Saving the Lives of Children

Dedicated Volunteer

Selected as one of five “Earthly Angels” for his efforts “fighting prejudice, hunger, homelessness, domestic violence and cancer” 

Dedicated Volunteer

Effective Public Servant

Dedicated Volunteer

 Former PTA President who created America’s 1st Green Certified PTA, Avid School Volunteer, Youth Sports Coach, and Lay Clergyman 

Effective Public Servant

Effective Public Servant

Effective Public Servant

Former Vice Chair of the Board of Education where he increased public involvement, digital education, six-sigma, and innovation 

Non-Profit Leader

Effective Public Servant

Effective Public Servant

Serving as President of the Ladera Ranch Education Foundation, the largest non-profit contributor to the local school district, which supports arts, music, and technology programs

BREAKING NEWS: MESHKIN VINDICATED, ALL CHARGES DISMISSED

OC Business Journal Covers Dismissal of All False Allegations

OC Business Journal Covers Dismissal of All False Allegations

OC Business Journal Covers Dismissal of All False Allegations

The allegations "resulted in the destruction of Proove Biosciences and the smearing of many reputations," Meshkin said. 

Read the OC Business Journal Article

OC Register Covers Dismissal of All False Allegations

OC Business Journal Covers Dismissal of All False Allegations

OC Business Journal Covers Dismissal of All False Allegations

The U.S. Attorney’s Office said in a court motion last week that it dismissed the case against Brian Javaade Meshkin, 46, “in the interests of justice.” The Ladera Ranch man, founder of Proove Biosciences Inc., was indicted in 2021, along with 8 other defendants on charges of conspiracy and receiving and making illegal payments.

Read the OC Register Article

Proove Biosciences CEO Exonerated in PGx Test Kickback Case

OC Business Journal Covers Dismissal of All False Allegations

Proove Biosciences CEO Exonerated in PGx Test Kickback Case

A federal judge in California has dismissed charges against the CEO of embattled genetic testing company Proove Biosciences who along with other individuals had been accused of paying physicians at least $3.5 million in kickbacks.


In a statement published Monday, Proove said, "These false allegations levied against Meshkin and Proove cause

A federal judge in California has dismissed charges against the CEO of embattled genetic testing company Proove Biosciences who along with other individuals had been accused of paying physicians at least $3.5 million in kickbacks.


In a statement published Monday, Proove said, "These false allegations levied against Meshkin and Proove caused tremendous harm, as they have been widely disseminated publicly and in the media. With this dismissal, the defendants are vindicated, and this flawed investigation has been thoroughly discredited."

Read the Genome Web Article

U.S. Government Soundly Defeated In Alleged Kickback Scheme

San Diego feds dismiss fraud case amid accusations over prosecutorial missteps

Proove Biosciences CEO Exonerated in PGx Test Kickback Case

By Kim Delmonico

The United States government was soundly defeated and forced to ask a Federal Judge to dismiss all charges against an innovative young California company and the clinics it serves.

The judge for the United States District Court in the Central District of California has issued an order granting the United States Government’s

By Kim Delmonico

The United States government was soundly defeated and forced to ask a Federal Judge to dismiss all charges against an innovative young California company and the clinics it serves.

The judge for the United States District Court in the Central District of California has issued an order granting the United States Government’s motion to dismiss all charges in a case involving physicians and other employees from Physical Medical Associates, Ltd., National Spine and Pain Center, LLC, and Proove Biosciences, Inc.


Proove is an Irvine, California-based biosciences company that specializes in the genetic testing of pain patients. According to the company, its “proprietary effective technology” includes “genetic tests and predictive software algorithms in its CLIA-certified, CAP-accredited state-of-the-art laboratory that helped doctors objectively assess pain, predict who would misuse opioids with up to 96.7% accuracy, and provide treatment insights which resulted in 50% pain reduction within 30 days of treatment changes, saving Medicare over $70 million annually.”

Read the Orthopedics in Review Article

Pain News Network Covers Exoneration

San Diego feds dismiss fraud case amid accusations over prosecutorial missteps

San Diego feds dismiss fraud case amid accusations over prosecutorial missteps

The U.S. Department of Justice has quietly dropped criminal charges against the founder and CEO of Proove Biosciences, a genetic testing company based in California that was accused of paying physicians over $3.5 million in illegal kickbacks. A judge dismissed the case against Brian Meshkin and five other defendants last month “in the int

The U.S. Department of Justice has quietly dropped criminal charges against the founder and CEO of Proove Biosciences, a genetic testing company based in California that was accused of paying physicians over $3.5 million in illegal kickbacks. A judge dismissed the case against Brian Meshkin and five other defendants last month “in the interests of justice” after federal prosecutors declined to move forward with the case. 

Read the Pain News Network Article

San Diego feds dismiss fraud case amid accusations over prosecutorial missteps

San Diego feds dismiss fraud case amid accusations over prosecutorial missteps

San Diego feds dismiss fraud case amid accusations over prosecutorial missteps

Jason de Bretteville, defense attorney for the lead defendant, Proove CEO Brian Meshkin, said the government attorneys never disclosed specifically why they sought a dismissal, but he speculated it was based on the case’s merits and “emerging issues relating to potential government misconduct.”


Meshkin said the decision to dismiss the case

Jason de Bretteville, defense attorney for the lead defendant, Proove CEO Brian Meshkin, said the government attorneys never disclosed specifically why they sought a dismissal, but he speculated it was based on the case’s merits and “emerging issues relating to potential government misconduct.”


Meshkin said the decision to dismiss the case was vindication for him and his co-defendants.

“There has been so much injustice over the past (six) years that it is wonderful to see truth prevail,” Meshkin wrote in a statement he sent to the Union-Tribune. “Ultimately, the facts spoke for themselves.”


Meshkin called the investigation a “foolish” waste of millions of taxpayer dollars that resulted from “misinformation spread by a handful of disgruntled ex-employees and contractors, spread by the media, and blindly adopted by some in the Southern District of California office of the U.S. Attorney and the FBI.”


Read the San Diego Union Tribune Article

Proove Biosciences CEO Exonerated in PGx Test Kickback Case

Proove Biosciences CEO Exonerated in PGx Test Kickback Case

Proove Biosciences CEO Exonerated in PGx Test Kickback Case

A federal judge in California has dismissed charges against the CEO of embattled genetic testing company Proove Biosciences.

Read 360Dx Article

Personal Statement from Brian Meshkin on the Vindication

Proove Biosciences CEO Exonerated in PGx Test Kickback Case

Proove Biosciences CEO Exonerated in PGx Test Kickback Case

“There has been so much injustice over the past 6 years that it is wonderful to see truth prevail.  I am excited to have the opportunity to set the record straight and to move forward from here with my head held high,”

Read Brian Meshkin's Personal Statement

Ink & THINK

Former Proove CEO Meshkin Starts Venture Fund: Plans lawsuits to fight “false allegations”

Former Proove CEO Meshkin Starts Venture Fund: Plans lawsuits to fight “false allegations”

Former Proove CEO Meshkin Starts Venture Fund: Plans lawsuits to fight “false allegations”

By Sherry Hseih, Healthcare Editor

Read the Article

Earthly Angels: In the season of comfort and joy, celebrate those who comfort in despair

Former Proove CEO Meshkin Starts Venture Fund: Plans lawsuits to fight “false allegations”

Former Proove CEO Meshkin Starts Venture Fund: Plans lawsuits to fight “false allegations”

 By Mary Corey 

Read the Article

He Felt Your Pain

Former Proove CEO Meshkin Starts Venture Fund: Plans lawsuits to fight “false allegations”

The genetic test that can help fix America's opioid painkiller addiction

By Vita Reed

Read the Article

The genetic test that can help fix America's opioid painkiller addiction

The genetic test that can help fix America's opioid painkiller addiction

The genetic test that can help fix America's opioid painkiller addiction

 By Jeniece Pettitt 

Watch the Report

Genetic test aims to identify people at risk for opioid addiction

The genetic test that can help fix America's opioid painkiller addiction

Genetic test aims to identify people at risk for opioid addiction

Watch the Report

A medical test that aims to wean Americans off painkillers

The genetic test that can help fix America's opioid painkiller addiction

Genetic test aims to identify people at risk for opioid addiction

By Dina Gusovsky

Watch the Report

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